Description
Antiserum to Human IgG (gamma chain specific) made in goat
IgG is the most abundant immunoglobulin in plasma, found at a concentration of 8 to 18 mg/ml. This immunoglobulin plays a very important role in the defense against infection for newborns because of its transfer through the placenta during pregnancy. It readily diffuses into the extravascular body spaces where it plays a major role in neutralizing bacterial toxins and in enhancing the phagocytosis of microorganisms. IgG binds to bacteria and these complexes adhere to phagocytic cells which have surface receptors specific for IgG.
Ref: Deisenhofer. J. 1981. Biochemistry. 20, 2361; Mehl, V.S. and Penn, G.M. 1986. Manual of Clinical Laboratory Immunology (N.R. Rose, ed.), 126.
Product Citations:
Baković, Maja Pučić, et al. "High-Throughput IgG Fc N-Glycosylation Profiling by Mass Spectrometry of Glycopeptides." Journal of proteome research 12, no. 2 (2013): 821-831
Smith, Loren E., et al. "Helical domains that mediate lipid solubilization and ABCA1-specific cholesterol efflux in apolipoproteins CI and A-II." Journal of lipid research 54, no. 7 (2013): 1939-1948.
Lee, Kyoung Ho, et al. "Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering." Applied microbiology and biotechnology(2013): 1-11.
Dolfi, Douglas V., et al. "Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged Humans." PLOS ONE 8, no. 10 (2013): e77164.
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