Description
Antiserum to Human IgE (epsilon chain specific) made in goat
IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior.
Product Citation:
Janssen, Kris PF, et al. "Multiplexed protein detection using an affinity aptamer amplification assay." Analytical and bioanalytical chemistry 404, no. 6-7 (2012): 2073-2081.
Schachermeyer, Samantha, et al. "Aptamer-Protein Binding Detected by Asymmetric Flow Field Flow Fractionation."Journal of Chromatography A (2013).
Abe, Takaaki, et al. "Antibody against immunoglobulin E contained in blood components as causative factor for anaphylactic transfusion reactions." Transfusion (2014).
Kashiwakura, Jun-ichi, et al. "Most highly cytokinergic IgEs have polyreactivity to autoantigens." Allergy, asthma & immunology research 4, no. 6 (2012): 332-340.
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