Description
Antiserum to Human Antithrombin III made in goat
Antithrombin III is found in normal serum at 15 mg per 100 ml. Found at higher levels in plasma than in serum because of complexing with thrombin during coagulation. Functions in the inhibition of the proteolytic enzymes involved in blood coagulation and fibrinolysis, including factor Xa, plasmin, thrombin, and trypsin. Potency is strongly enhanced by heparin. Clinically, reduced levels are indicative of hypercoagulability.
Product Citation: Perera, Natascha C., Oliver Schilling, Heike Kittel, Walter Back, Elisabeth Kremmer, and Dieter E. Jenne. "NSP4, an elastase-related protease in human neutrophils with arginine specificity. Proceedings of the National Academy of Sciences 109, no. 16 (2012): 6229-6234.